CryoPen B+ for the treatment of plantar warts

A treatment method that uses a fine jet of nitrous oxide under high pressure.

3 applicators included:
- Ø ? 1-4mm: power **
- Ø ?? 2-6mm: power ****
- Ø ? 4-8mm: power ******

CryoPen guaranteed for 5 years and applicator for 2 years

The manufacturer undertakes to train you via video call.

This device works to remove warts from your patients without any pain and replaces Vercid which is not always 100% effective.
You can offer your patients a CryoPen package of 2 to 3 sessions with an interval of 7 to 10 days.

Positioning the CryoPen instrument for treatment
The instrument should be held vertically with the tip pointing downwards. An angle less than 45° should be avoided.

Effective application
Before starting treatment, consider the age, location, size and number of lesions, skin type, degree of tanning and season.
The tip of the applicator (from which the liquefied N?O is released) should be kept at a distance of 0.5 to 3 mm from the lesion. A distance greater than 5 mm between the lesion and the tip of the applicator will result in the liquid N?O becoming gaseous, making it ineffective in terms of therapeutic results.

As you approach the stream to the lesion, you can observe the focal point of the jet on the tissue. The closer you get to the lesion, the greater the cryogenic power applied to the tissue. For smaller lesions and more delicate operations, we recommend increasing the distance.
Control the amount of liquid N?O to be applied by quick back and forth movements of the applicator.
Circular and crisscross movements have the same effect.

Condensation of moisture in the air can, in some cases, cause ice to form on the lesion.
This “ice igloo” will hinder the efficient operation of the liquid phase of the cryogen (at -89°C) and must be removed.
The learning curve for using the CryoPen is short. CryoPen allows for complete control when applying cryogen. Start by treating common injuries, and as you gain experience, move on to more delicate injuries.

Duration/depth of treatment
Hold the tip of the applicator as close to the lesion as possible.
Typical freezing for viral lesions can take 5 to 10 seconds for small flat warts and up to 45 seconds for full-thickness plantar warts.
For most lesions, treatment time is between 2 and 30 seconds.
This duration depends on the surface area and thickness of the tissue being treated. To estimate the thickness, the practitioner should rely on clinical experience. After the first freezing cycle, allow the tissue to thaw for approximately 30 seconds, followed by a second cryogenic treatment.
Note that during this second cycle, the tissue will freeze faster than during the first cycle. This "freeze-thaw-freeze" technique offers the best chance of success. You will find this procedure in most scientific articles on cryotherapy.
A follow-up visit is recommended after 2 to 4 weeks, to confirm the disappearance of all pathological tissue and to verify whether or not follow-up treatment is necessary.

The user manual is available in the "attachments" tab above??

Use of the instrument:
Step 1 : Loading a new cartridge
The cartridges are packaged in peel-off blister packs with an assembled filter/piercer. The filters are used to protect the applicator, and the perforator is used to pierce the cartridge.
CryoPen X+ and CryoPen XP can be used with both 16g and 8g N?O cartridges, thanks to the 8/16g converter. Check that the cavity contains no residual material.
Open the peel-off packaging. Remove the filter/piercer with tweezers. Hold the end of the CryoPen facing downwards. Place the filter/piercer into the instrument, ensuring it is flat at the bottom of the loading cavity.
The perforator trocar should be pointing upwards! Take the cartridge and insert it into the cavity, narrow side down, above the filter/perforator.

Step 2: Puncture the unused cartridge
Carefully screw the posterior end of the CryoPen onto the anterior end.
Continue until you feel contact between the filter/perforator unit and the cartridge. Then position your hands so that you can perform one final rotation without interruption. Then turn quickly until you reach the stop.
You may eventually hear a short hissing sound.
The shorter the better!

Extracting the used cartridge and emptying the cavity
Before loading a new cartridge, first release all residual gas from the cartridge by unscrewing the applicator and then pressing the trigger. Then unscrew the rear end. Discard the used cartridge and filter/perforator.
For CryoPen X+ and CryoPen XP instruments, be careful not to throw away the 16/8 g converter.
Make sure that the used filter/perforator does not remain in the cavity. The cavity must no longer contain any items.

Step 3: Using your CryoPen
Remove the applicator cap. Gently press the trigger to start the flow of N?O. Release the trigger to stop the flow of cryogenic liquid.
1 or 2 seconds after releasing the trigger, the gas remaining in the applicator is released.
One cartridge can be used for multiple treatments and patients.

Important notes:

Make sure to only use cartridges and filters/perforators supplied by H&O Equipments nv/sa. Any other cartridges and filters/perforators will damage the instrument.
Incorrect positioning of the filter/perforator device in the loading cavity will cause irreversible damage to the instrument.
Residual foreign matter present in the loading cavity when inserting a new filter/perforator may cause instrument failure.
The loaded instrument is under high pressure. Any changes to the structure of the instrument may result in a potential hazard.
Never obstruct the gas expulsion opening with your hand, at the end of the rear part, when removing the cartridge!
Cartridges should be kept away from heat (max 50°C/122°F). Keep the applicator cap on when not in use.
CryoPen instruments are for professional use only.
N2O cartridges contain both a liquid and a gas phase in equilibrium. The proportion of each of these phases depends on the ambient temperature and influences the output flow rate. Best performance is achieved when the cartridge temperature is between 19°C and 22°C. Lower or higher temperatures will result in different pressure and density values of the cryogenic substance. Above 25°C, the amount of liquefied N2O in the CryoPen jet will decrease.
Empty cartridges should be disposed of with metal waste.

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